Theta Rhythmic Clock-Like Activity of Single Units in the Mouse Hippocampus.
Lu ZhangXiaoyu MaGuifen ChenEdi BarkaiLongnian LinPublished in: The Journal of neuroscience : the official journal of the Society for Neuroscience (2016)
Theta oscillations, as the predominant rhythms in the hippocampus during waking exploration and rapid eye movement sleep, may be critical for temporal coding/decoding of neuronal information, and theta-phase precession in hippocampal place cells is one of the best demonstrations of such temporal coding. Here, we show that a unique small class of hippocampal CA1 neurons fired with a theta rhythmic clock-like firing pattern during theta states. These firing characteristics support the notion that these neurons may play a critical role in theta-related temporal coding in the hippocampus.
Keyphrases
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- working memory
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- induced apoptosis
- subarachnoid hemorrhage
- brain injury
- blood brain barrier
- cell proliferation
- spinal cord injury
- cell cycle arrest
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- protein kinase
- loop mediated isothermal amplification
- drug induced