The impact of obesity and endocrine therapy on the prognosis of premenopausal women with hormone receptor-positive breast cancer: A single-institute retrospective study.
Yukinori OzakiJun MasudaAkemi KataokaTakahiro KogawaTomomi AbeHidetomo MorizonoLina InagakiFumikata HaraToshimi TakanoTakayuki UenoShinji OhnoPublished in: Cancer reports (Hoboken, N.J.) (2022)
High BMI was associated with worse prognosis in premenopausal patients with HR-positive BC who received adjuvant TAM. The role of OFS as adjuvant endocrine therapy remains unclear, and further studies are required to explore the adequate management of obese premenopausal patients.
Keyphrases
- positive breast cancer
- postmenopausal women
- metabolic syndrome
- end stage renal disease
- early stage
- weight loss
- type diabetes
- newly diagnosed
- ejection fraction
- chronic kidney disease
- insulin resistance
- adipose tissue
- weight gain
- body mass index
- prognostic factors
- breast cancer risk
- stem cells
- cell therapy
- bone marrow
- obese patients
- patient reported outcomes
- patient reported