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Development of a Validated Stability-Indicating HPLC Method for Vinpocetine in the Presence of Potential Impurities in Tablet Dosage Form by Multiresponse Optimization.

Özlem KaraerŞule Dinç-ZorBürge Aşçı
Published in: Journal of AOAC International (2022)
A reliable and rapid HPLC method optimized with response surface methodology and multiresponse optimization based on Derringer's desirability function was developed for the simultaneous analysis of vinpocetine and its impurities in a tablet formulation.
Keyphrases
  • ms ms
  • simultaneous determination
  • high performance liquid chromatography
  • solid phase extraction
  • mass spectrometry
  • tandem mass spectrometry
  • drug delivery
  • liquid chromatography
  • human health