High cut-off membrane for in-vivo dialysis of free plasma hemoglobin in a patient with massive hemolysis.

Clearance of CPH through a HCO filter is technically feasible but its performance markedly relies on the initial concentration of CPH. Critically ill patients with smoldering hemolysis, as it happens during septic shock or ECMO treatment, may benefit the most from the use of this membrane in order to clear CPH.