Hyaluronan induces odontoblastic differentiation of dental pulp stem cells via CD44.
Naoki UmemuraEmika OhkoshiMasamichi TajimaHirotaka KikuchiTadashi KatayamaHiroshi SakagamiPublished in: Stem cell research & therapy (2016)
Our results indicate that hyaluronan induces odontoblastic differentiation of DPSCs via CD44. This suggests that hyaluronan plays a crucial role in the induction of odontoblastic differentiation from DPSCs. Our findings may aid the development of new, inexpensive, and effective conservative treatments for dental pulp repair.