Plasma Proteomics Study Between the Frequent Exacerbation and Infrequent Exacerbation Phenotypes of Chronic Obstructive Pulmonary Disease.

Chengyu YangLi YangLei YangShuiming LiLing YeJinfeng YeChengshui ChenYiming ZengMengchan ZhuXiaoping LinQing PengYun WangMeiling Jin

Published in: International journal of chronic obstructive pulmonary disease (2023)

In this study, novel insights into COPD pathogenesis were provided by investigating and comparing plasma protein profiles between the FE and IE patients. CKM, FITM1, and a combinative biomarker panel may serve as useful tools for assisting in the precision diagnosis and effective treatment of the FE phenotype of COPD.

Keyphrases

chronic obstructive pulmonary disease
end stage renal disease
lung function
newly diagnosed
chronic kidney disease
prognostic factors
patient reported outcomes
extracorporeal membrane oxygenation
binding protein
smoking cessation
mechanical ventilation