Time-dependent antiarrhythmic effects of flecainide on induced atrial fibrillation in horses.
Helena CarstensenEva Z HesselkildeMerle FennerAmeli V Loft-AndersenMette FlethøjJørgen K KantersStefan M SattlerJacob Tfelt-HansenSteen PehrsonThomas JespersenRikke BuhlPublished in: Journal of veterinary internal medicine (2018)
Flecainide is effective for cardioversion of short-term induced AF, but the effect decreases with AF duration. Controlling heart rate may minimize adverse effects caused by flecainide, but the drug should be used with great caution.
Keyphrases
- atrial fibrillation
- heart rate
- catheter ablation
- high glucose
- diabetic rats
- heart rate variability
- blood pressure
- oral anticoagulants
- left atrial
- drug induced
- heart failure
- left atrial appendage
- direct oral anticoagulants
- oxidative stress
- percutaneous coronary intervention
- coronary artery disease
- mitral valve
- venous thromboembolism