Early initiation of prophylactic anticoagulation for prevention of COVID-19 mortality: a nationwide cohort study of hospitalized patients in the United States.
Christopher T RentschJoshua A BeckmanLaurie TomlinsonWalid F GelladCharles AlcornFarah Kidwai-KhanMelissa SkandersonFrank E HarrellJoseph T KingYuk-Lam HoSvetlana K EdenSuman KunduMichael F LannRobert A GreevyP Michael HoPaul A HeidenreichDaniel A JacobsonIan J DouglasJanet P TateStephen Jw EvansDavid AtkinsAmy C JusticeMatthew S FreibergPublished in: medRxiv : the preprint server for health sciences (2020)
Early initiation of prophylactic anticoagulation among patients hospitalized with COVID-19 was associated with a decreased risk of mortality. These findings provide strong real-world evidence to support guidelines recommending the use of prophylactic anticoagulation as initial therapy for COVID-19 patients upon hospital admission.