Recovery of adrenal function after stopping mitotane in patients with adrenocortical carcinoma.
Barbara AltieriOtilia KimpelFelix MegerleMario DetomasIrina ChifuCarmina Teresa FussMarcus QuinklerMatthias KroissFassnacht MartinPublished in: European journal of endocrinology (2024)
Our study demonstrates that adrenal recovery occurs in most patients after stopping mitotane, particularly when followed up in specialized centers, but not in all. Elimination time of mitotane after treatment discontinuation is very long but individually quite variable.