The prevalence of bronchiectasis in patients with alpha-1 antitrypsin deficiency: initial report of EARCO.

Robert A StockleyAnita PyeJoshua De SoyzaAlice M TurnerMarc Miravitllesnull null

Published in: Orphanet journal of rare diseases (2023)

The data indicates the bronchiectasis alone is a feature of 9.1% of patients with the PiZZ genotype of Alpha1-antitrypsin deficiency but although emphysema is the dominant lung pathology bronchiectasis is also present in 27% of emphysema cases and may require a different treatment strategy.

Keyphrases

cystic fibrosis
lung function
chronic obstructive pulmonary disease
replacement therapy
pulmonary fibrosis
risk factors
idiopathic pulmonary fibrosis
machine learning
electronic health record
deep learning
big data
combination therapy
artificial intelligence
data analysis