Login / Signup

Comparative Tumor Microenvironment Analysis of Primary and Recurrent Ovarian Granulosa Cell Tumors.

Eleonora Yu KhlebusVeena K VuttaradhiThomas WelteNamrata KhuranaJoseph CelestinoHannah C BeirdCurtis GumbsLatasha LittleAlejandra Flores LegarretaBryan M FellmanTri NguyenBarrett C LawsonSammy Ferri-BorgognoSamuel C MokRussell R BroaddusDavid M GershensonP Andrew FutrealRobert Tyler Hillman
Published in: Molecular cancer research : MCR (2023)
Recurrent aGCTs exhibit alterations in hormone pathway gene expression as well as decreased infiltration of cancer-associated fibroblasts, suggesting dual roles for hormonal signaling and TME remodeling underpinning disease relapse.
Keyphrases
  • gene expression
  • polycystic ovary syndrome
  • single cell
  • dna methylation
  • cell therapy
  • stem cells
  • extracellular matrix
  • free survival
  • type diabetes
  • adipose tissue
  • mesenchymal stem cells