Validity of tissue homogeneity in confocal laser endomicroscopy on the diagnosis of laryngeal and hypopharyngeal squamous cell carcinoma.

Matti SievertMarc AubrevilleAntoniu-Oreste GostianKonstantinos MantsopoulosMichael KochSarina Katrin MuellerMarkus EcksteinRobin RuppFlorian StelzleNicolai OetterAndreas MaierHeinrich IroMiguel Goncalves

Published in: European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery (2022)

SCC shows a significant tissue inhomogeneity in comparison to the healthy epithelium. The results support this feature's importance in identifying malignant mucosa areas during CLE examination. However, the examiner-dependent evaluation emphasizes that homogeneity is a sub-criterion that must be considered in a broad context.

Keyphrases

squamous cell carcinoma
machine learning
deep learning
optical coherence tomography
lymph node metastasis
locally advanced
mass spectrometry
high resolution
rectal cancer