Pleomorphic adenoma and carcinoma ex-pleomorphic adenoma tumorigenesis: A proteomic analysis.
Virgilio Gonzales ZanellaSara Ferreira Dos Santos CostaLauren Frenzel SchuchEmily Ferreira Salles PilarAdriana Franco Paes LemeJean Nunes Dos SantosSyed Ali KhurramFatima ElalawyLynne BingleFabio Daumas NunesFlávia Sirotheau Correa PontesPablo Agustin VargasManoela Domingues MartinsVivian Petersen WagnerPublished in: Oral diseases (2024)
Proteomic analysis identified differential protein expression patterns associated with malignant transformation of PA into CXPA. Findings indicate a crucial role for extracellular matrix proteins, specifically Biglycan and Decorin, in the tumorigenic progression of PA and CXPA.
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