Therapeutic inhibition of microRNA-21 (miR-21) using locked-nucleic acid (LNA)-anti-miR and its effects on the biological behaviors of melanoma cancer cells in preclinical studies.
Shaghayegh Haghjooy JavanmardGolnaz VaseghiAhmad GhasemiLaleh RafieeGordon A FernsHajar Naji EsfahaniReza NedaeiniaPublished in: Cancer cell international (2020)
Our findings suggest LNA-anti-miR-21 can be potentially used as an anticancer agent for the treatment of melanoma.