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Therapeutic inhibition of microRNA-21 (miR-21) using locked-nucleic acid (LNA)-anti-miR and its effects on the biological behaviors of melanoma cancer cells in preclinical studies.

Shaghayegh Haghjooy JavanmardGolnaz VaseghiAhmad GhasemiLaleh RafieeGordon A FernsHajar Naji EsfahaniReza Nedaeinia
Published in: Cancer cell international (2020)
Our findings suggest LNA-anti-miR-21 can be potentially used as an anticancer agent for the treatment of melanoma.
Keyphrases
  • cell proliferation
  • long non coding rna
  • nucleic acid
  • long noncoding rna
  • stem cells
  • mesenchymal stem cells
  • bone marrow
  • smoking cessation
  • basal cell carcinoma