Stress decreases spermatozoa quality and induces molecular alterations in zebrafish progeny.
David G ValcarceMarta F RiescoLeyre Cuesta-MartínAnna Esteve-CodinaJuan Manuel Martínez-VázquezVanesa RoblesPublished in: BMC biology (2023)
Induction of chronic stress during a few cycles of spermatogenesis in the vertebrate zebrafish model affects behavior, gonadal gene expression, final gamete quality, and progeny. The NMD surveillance pathway (a key cellular mechanism that regulates the stability of both normal and mutant transcripts) is severely affected in the testes by chronic stress and therefore the control and regulation of RNAs during spermatogenesis may be affected altering the molecular status in the progeny.