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Hyaluronan-Based Gel Promotes Human Dental Pulp Stem Cells Bone Differentiation by Activating YAP/TAZ Pathway.

Marcella La NoceAntonietta StellavatoValentina VassalloMarcella CammarotaLuigi LainoVincenzo DesiderioVitale Del VecchioGiovanni Francesco NicolettiVirginia TirinoGianpaolo PapaccioChiara SchiraldiGiuseppe Andrea Ferraro
Published in: Cells (2021)
We found that HA's molecular weight can have a relevant impact on HA performance for bone regeneration, and we unveil a new molecular mechanism by which HA acts on stem cells.
Keyphrases
  • stem cells
  • bone regeneration
  • endothelial cells
  • signaling pathway
  • cell therapy
  • induced pluripotent stem cells
  • bone mineral density
  • mesenchymal stem cells