Drug Resistance in Tuberculous Lymphadenitis: Molecular Characterization.
Gebeyehu Assefa MitikuKassu DestaShambel ArayaSelfu GirmaElena HailuAdane MihretTsegaye HailuMelaku TilahunGetu DiribaBiniyam DagneAbay AtnafuNigatu EndalaferAdugna AberaShiferaw BekeleYordanos MengistuKidist BoboshaAbraham AseffaPublished in: Tuberculosis research and treatment (2023)
The predominance of INH mono-resistance poses a critical risk for the potential development of MDR-TB, as INH mono-resistance is a typical pathway to the occurrence of MDR-TB. The orphan and SIT53 (T) strains were the most common in the study area, and a drug-resistant strain caused by a common gene mutation could indicate the transmission of clonal-resistant strains in the community.