Intensity-dependent gamma electrical stimulation regulates microglial activation, reduces beta-amyloid load, and facilitates memory in a mouse model of Alzheimer's disease.

Qian LiuAdam ContrerasMuhammad Shan AfaqWeijian YangDaniel K HsuMichael RussellBruce LyethTheodore P ZantoMin Zhao

Published in: Cell & bioscience (2023)

The efficacy of GES on the reduction of AD pathology and the intensity-dependent feature provide guidance for the development of this promising therapeutic approach.

Keyphrases

mouse model
high intensity
spinal cord injury
machine learning
inflammatory response
deep learning
cognitive decline
working memory
lps induced
neuropathic pain
spinal cord