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Soluble CD127 potentiates IL-7 activity in vivo in healthy mice.

Nawaf A AloufiAlaa K AliStephanie C Burke SchinkelBengisu MolyerPriscila O BarrosJoanne E McBaneSeung-Hwan LeeJonathan B Angel
Published in: Immunity, inflammation and disease (2021)
These findings suggest that the addition of sCD127 enhances IL-7-mediated T-cell proliferation and suggests a potential therapeutic use for sCD127.
Keyphrases
  • cell proliferation
  • cell cycle
  • high fat diet induced
  • signaling pathway