Cerebrospinal fluid-related tissue damage in multiple sclerosis patients with iron rim lesions.

Matthias WittayerClaudia E WeberMaximilian KittelMichael PlattenLucas SchirmerHayrettin TumaniAchim GassPhilipp Eisele

Published in: Multiple sclerosis (Houndmills, Basingstoke, England) (2023)

IRLs are associated with higher intrathecal IgG synthesis. CSF-mediated intrathecal smouldering inflammation could explain a CSF-related gradient of tissue damage.

Keyphrases

cerebrospinal fluid
oxidative stress
multiple sclerosis
white matter