Role of Nutrient-sensing Receptor GPRC6A in Regulating Colonic Group 3 Innate Lymphoid Cells and Inflamed Mucosal Healing.

Bingkun ZhangJingxi HuangXia XiongYuming GuoBingkun Zhang

Published in: Journal of Crohn's & colitis (2022)

Our findings unveil a role for the nutrient-sensing receptor GPRC6A in colonic ILC3 function and identify a novel ILC3 receptor signalling pathway modulating inflamed mucosal healing.

Keyphrases

ulcerative colitis
induced apoptosis
signaling pathway
binding protein
pi k akt