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EXPANSION: a webserver to explore the functional consequences of protein-coding alternative splice variants in cancer genomics.

Chakit AroraNatalia De Oliveira RosaMarin MaticMariastella CasconePasquale MiglionicoFrancesco Raimondi
Published in: Bioinformatics advances (2023)
EXPANSION is freely available at http://expansion.bioinfolab.sns.it/. The code of the scripts used for EXPASION is available at: https://github.com/raimondilab/expansion. Datasets associated to this resource are available at the following URL: https://doi.org/10.5281/zenodo.8229120. The web-server was developed using Apache2 (https://https.apache.org/) and Flask (v2.0.2) (http://flask.pocoo.org/) for the web frontend and for the internal pipeline to handle back-end processes. We additionally used the following Python and JavaScript libraries at both back- and front-ends: D3 (v4), jQuery (v3.2.1), DataTables (v2.3.2), biopython (v1.79), gprofiler-officia l(v1.0.0), Mysql-connector-python (v8.0.31). To construct the API, Fast API library (v0.95.1) was used.
Keyphrases
  • protein protein
  • gene expression
  • squamous cell
  • small molecule
  • dna methylation
  • rna seq
  • genome wide