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In Silico Analysis of Bioactive Peptides in Invasive Sea Grass Halophila stipulacea.

Cagin Kandemir-CavasHoracio Pérez SánchezNazli Mert-OzupekLevent Çavaş
Published in: Cells (2019)
Halophila stipulacea is a well-known invasive marine sea grass in the Mediterranean Sea. Having been introduced into the Mediterranean Sea via the Suez Channel, it is considered a Lessepsian migrant. Although, unlike other invasive marine seaweeds, it has not demonstrated serious negative impacts on indigenous species, it does have remarkable invasive properties. The present in-silico study reveals the biotechnological features of H. stipulacea by showing bioactive peptides from its rubisc/o protein. These are features such as antioxidant and hypolipideamic activities, dipeptidyl peptidase-IV and angiotensin converting enzyme inhibitions. The reported data open up new applications for such bioactive peptides in the field of pharmacy, medicine and also the food industry.
Keyphrases
  • angiotensin converting enzyme
  • amino acid
  • angiotensin ii
  • molecular docking
  • oxidative stress
  • minimally invasive
  • climate change
  • binding protein
  • molecular dynamics simulations
  • human health