Detection of MET gene somatic mutations in hepatocellular carcinoma of Egyptian patients using next-generation sequencing.
Ehab AhmedNour El-Dien ASalwa SabetMohamed KhalifaManal El HamsharyPublished in: Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals (2023)
Screening of the targeted genes such as c-MET for potential mutations is very important in the determination of the appropriate therapy. Therefore, it can be used as a biomarker in the prognosis of HCC. Such screenings are also of paramount importance in the development of personalised medicine.
Keyphrases
- copy number
- end stage renal disease
- genome wide
- newly diagnosed
- ejection fraction
- tyrosine kinase
- chronic kidney disease
- genome wide identification
- peritoneal dialysis
- prognostic factors
- gene expression
- cancer therapy
- mesenchymal stem cells
- dna methylation
- mass spectrometry
- solid phase extraction
- label free
- molecularly imprinted
- drug delivery
- sensitive detection
- circulating tumor cells
- bioinformatics analysis