Genetic Alterations Predict Long-Term Survival in Ductal Adenocarcinoma of the Pancreatic Head.

Sami Alexander Safi Lena HäberleWolfgang GoeringVerena KeitelGeorg Fluegen Nikolas H StoeckleinAlexander RehdersWolfram Trudo KnoefelIrene Esposito

Published in: Cancers (2022)

NGS of PDAC revealed significant differences in survival outcome in a patient collective with homogenously distributed clinicopathological variables. Further multi-institutional studies are warranted to identify more long-term survivors to detect genetic differences suitable for targeted therapy.

Keyphrases

genome wide
copy number
squamous cell carcinoma
case report
young adults
dna methylation
radiation therapy
locally advanced