Single-cell analysis characterizes PLK1 as a promoter of immunosuppressive tumor microenvironment in LUAD.

Yifan KongChaohao LiJinpeng LiuMin ZhangDerek B AllisonFaisal HassanDaheng HeXinyi WangFengyi MaoQiongsi ZhangYanquan ZhangZhiguo LiSai WuChi WangXiaoqi Liu

Published in: bioRxiv : the preprint server for biology (2023)

The characterization of PLK1 as a promoter of immunosuppressive tumor microenvironment enhances our understanding of PLK1's role in anti-tumor immunity and supports the idea of targeting PLK1 in cancer treatment.

Keyphrases

single cell
dna methylation
transcription factor
gene expression
high throughput
cancer therapy
drug delivery