Plasma Metabolomics Reveals Steroidal Alkaloids as Novel Biomarkers of Tomato Intake in Mice.
Morgan J CichonKen M RiedlLei WanJennifer M Thomas-AhnerDavid M FrancisSteven K ClintonSteven J SchwartzPublished in: Molecular nutrition & food research (2017)
Dietary tomato glycoalkaloids are cleaved during digestion to aglycones and further metabolized post-absorption. Steroidal alkaloids in plasma may serve as novel and specific biomarkers of tomato consumption and represent a class of phytochemical metabolites that could potentially have in vivo bioactivity impacting health and disease processes.