Snoring and risk of dementia: a prospective cohort and Mendelian randomization study.

Yaqing GaoShea J AndrewsWilla BrenowitzCyrus A RajiKristine YaffeYue Leng

Published in: medRxiv : the preprint server for health sciences (2023)

The phenotypic association between snoring and lower dementia risk likely stems from reverse causation, with genetic predisposition to AD associated with reduced snoring. This may be driven by weight loss in prodromal AD.

Keyphrases

mild cognitive impairment
weight loss
cognitive impairment
bariatric surgery
genome wide
roux en y gastric bypass
copy number
dna methylation
adipose tissue