Efficacy of cotrimoxazole (Sulfamethoxazole-Trimethoprim) as a salvage therapy for the treatment of bone and joint infections (BJIs).

Laurene DeconinckAurélien DinhChristophe NichThomas TritzMorgan MattOlivia SenardSimon BessisThomas BauerMartin RottmanJérome SalomonFrédérique BouchandBenjamin Davido

Published in: PloS one (2019)

SXT appears to be effective for treatment of BJIs as a salvage therapy, even in GNB or polymicrobial infection, including ODI. Further data are needed to confirm SXT efficacy as an alternative oral regimen in BJIs.

Keyphrases

combination therapy
bone mineral density
bone marrow
microbial community