Pro-inflammatory cytokines stimulate CFTR-dependent anion secretion in pancreatic ductal epithelium.
Dora AngyalTessa A GroenewegAnny LeungMax DesainKalyan DullaHugo R de JongeMarcel J C BijveldsPublished in: Cellular & molecular biology letters (2024)
Pro-inflammatory cytokines enhance CFTR-dependent anion secretion across pancreatic ductal epithelium. We propose that up-regulation of CFTR in the early stages of the inflammatory response, may serve to promote the removal of pathogenic stimuli from the ductal tree, and limit tissue injury.