Antibacterial activity of high-dose nitric oxide against pulmonary Mycobacterium abscessus disease.

Kristijan Bogdanovski Trisha ChauChevalia J RobinsonSandra D MacDonaldAnn M PetersonChristine M MashekWindy A WallinMark RimkusFrederick MontgomeryJoas Lucas da SilvaShashank GuptaAbdi GhaffariAdrian M ZelaznyKenneth N Olivier

Published in: Access microbiology (2020)

These results demonstrate heterogeneity in M. abscessus susceptibility to NO and suggest that longer treatment regimens could be required to see the reduction or eradication of more resistant pulmonary strains.

Keyphrases

high dose
nitric oxide
pulmonary hypertension
escherichia coli
mycobacterium tuberculosis
low dose
helicobacter pylori infection
nitric oxide synthase
combination therapy