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Time to recovery and its predictors among adults hospitalized with COVID-19: A prospective cohort study in Ethiopia.

Saro Abdella AbrahimMasresha TessemaAtkure DefarAlemayehu HussenEshetu E ChakaGetachew DemozAddisu Birhanu TeredaEnatenesh DillnessaAltaye FelekeMisiker AmareFrehiwot NigatuYaregal FufaHailu ReferaAyalew AkliluMunir KassaTsigereda KifleSusan WhitingGetachew TolleraEbba Abate
Published in: PloS one (2020)
A total of 306 COVID-19 cases were followed up to observe the duration of viral clearance by rRT-PCR. Participants' mean age was 34 years (18-84 years) and 69% were male. The median duration of viral clearance from each participant's body was 19 days, but the range was wide: 2 to 71 days. Cough followed by headache was the leading sign of illness among the 67 symptomatic COVID-19 patients; and nearly half of those with comorbidities were known cancer and HIV/AIDS patients on clinical follow up. The median duration of recovery from COVID-19 was different for those with and without previous medical conditions or comorbidities. The rate of recovery from SARS-CoV-2 infection was 36% higher in males than in females (p = 0.043, CI: 1.01, 1.85). The rate of recovery was 93% higher in those with at least one comorbidity than in those without any comorbidity. The risk of delayed recovery was not influenced by blood type, BMI and presence of signs or symptoms. The findings showed that study participants without comorbidities recovered more quickly than those with at least one comorbidity. Therefore, isolation and treatment centers should be prepared to manage the delayed stay of patients having comorbidity.
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