Herpes simplex virus and rates of cognitive decline or whole brain atrophy in the Dominantly Inherited Alzheimer Network.
Charlotte Warren-GashSharon L CadoganJennifer M NicholasJudith M BreuerDivya ShahNeil PearceSuhail ShiekhLiam SmeethMartin R FarlowHiroshi MoriBrian A GordonGeorg S NueblingEric McDadeRandall J BatemanPeter R SchofieldJae-Hong LeeJohn C MorrisDavid M CashNick C FoxBasil H RidhaMartin N Rossornull nullPublished in: Annals of clinical and translational neurology (2022)
We found no evidence for a major role of HSV-1, measured by serum antibodies, in cognitive decline or whole brain atrophy among individuals at high risk of early-onset AD.