Genetic Testing Distinguishes Multiple Chondroid Chordomas with Neuraxial Bone Metastases from Multicentric Tumors.
Hiroshi KobayashiMasahiro ShinNaohiro MakiseAya Shinozaki-UshikuMasachika IkegamiYuki TaniguchiYusuke ShinodaShinji KohsakaTetsuo UshikuKatsutoshi OdaKiyoshi MiyagawaHiroyuki AburataniHiroyuki ManoSakae TanakaPublished in: Case reports in genetics (2020)
The present evidence indicates that multiple chordomas in this case were caused by multiple metastases rather than multicentric lesions. Multiple presentations of chordoma imply systemic dissemination of tumor cells, and novel efficient systemic therapy is required to treat this disease.
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