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Preserved T-cell response in anti-CD20-treated multiple sclerosis patients following SARS-CoV-2 vaccination.

Simon FaissnerNeele HeitmannRicarda RohlingUlas CeylanMarielena BongertCarlos Plaza-SirventCorinna MarheineckeXiomara PedreiturriaIlya AyzenbergKerstin HellwigIngo SchmitzStephanie PfaenderRalf Gold
Published in: Therapeutic advances in neurological disorders (2022)
In summary, aCD20-treated patients have a reduced humoral immune response, depending on B cell repopulation, in accordance with preserved cellular immune response, suggesting partial cellular protection against SARS-CoV-2.
Keyphrases
  • immune response
  • sars cov
  • newly diagnosed
  • multiple sclerosis
  • end stage renal disease
  • ejection fraction
  • toll like receptor
  • nk cells