Genetic biomarkers for intravenous immunoglobulin response in chronic inflammatory demyelinating polyradiculoneuropathy.

Krista KuitwaardPieter A van DoornThiziri BengrineWouter van RijsFrank BaasSietse Q NagelkerkeTaco W KuijpersWillem-Jan R FokkinkCarina Bunschoten Merel C BroersSten P WillemsenBart C JacobsRuth Huizinga

Published in: European journal of neurology (2021)

Variations in PRF1 and the promoter region of FCGR2B are associated with the response to IVIg in CIDP. These findings, which require validation, are a first step towards the understanding of the heterogeneity in the treatment response in CIDP.

Keyphrases

dna methylation
genome wide
single cell
high dose
oxidative stress
gene expression
transcription factor
copy number