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Proteomic and metabolomic signatures of U87 glioblastoma cells treated with cisplatin and/or paclitaxel.

Munazza AhmedAhlam M SemreenAlexander D GiddeyWafaa S RamadanRaafat El-AwadyNelson Cruz SoaresWaseem El-HuneidiYasser K BustanjiMohammad A Y AlqudahKarem H AlzoubiMohammad Harb Semreen
Published in: Annals of medicine (2024)
Our research provides a detailed map of alterations in response to cisplatin and paclitaxel treatment, provides crucial insights into the molecular basis of their action, and paves the way for further research to identify molecular targets for this elusive malignancy.
Keyphrases
  • induced apoptosis
  • cell cycle arrest
  • genome wide
  • oxidative stress
  • dna methylation
  • signaling pathway
  • combination therapy
  • label free