Rapid DNA methylation-based classification of pediatric brain tumors from ultrasonic aspirate specimens.

Michèle Simon Luis P Kuschel Katja von Hoff Dongsheng Yuan Pablo Hernáiz Driever Elisabeth G HainArend KochDavid Capper Matthias Schulz Ulrich Wilhelm Thomale Philipp Euskirchen

Published in: Journal of neuro-oncology (2024)

Methylation-based classification of pediatric CNS tumors based on ultrasonic aspirator-reduced and otherwise discarded tissue is feasible using time- and cost-efficient nanopore sequencing.

Keyphrases

dna methylation
machine learning
deep learning
genome wide
gene expression
blood brain barrier
copy number
childhood cancer