Targeted fusion analysis can aid in the classification and treatment of pediatric glioma, ependymoma, and glioneuronal tumors.

Jessica A LakeAndrew M DonsonEric PrinceKurtis D DaviesAnandani NellanAdam L GreenJean Mulcahy LevyKathleen DorrisRajeev VibhakarTodd C HankinsonNicholas K ForemanMark D EwaltBette K Kleinschmidt-DeMastersLindsey M HoffmanAhmed Gilani

Published in: Pediatric blood & cancer (2019)

Fusion testing proved to be informative in a high percentage of cases. A large majority of fusion events in pediatric glial, glioneuronal, and ependymal tumors can be identified by relatively small gene panels.

Keyphrases

machine learning
deep learning
genome wide
copy number
gene expression
spinal cord injury
genome wide identification
data analysis