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Genetic determinants of immune-related adverse events in patients with melanoma receiving immune checkpoint inhibitors.

Noha Abdel-WahabAdi DiabRobert K YuAndrew FutrealLindsey A CriswellJean H TayarRamona DaduVickie ShannonSanjay S SheteMaria E Suarez-Almazor
Published in: Cancer immunology, immunotherapy : CII (2021)
Several genetic variants associated with irAEs were identified. Additional larger studies are needed to validate these findings and establish their potential functional relevance.
Keyphrases
  • genome wide
  • case control
  • copy number
  • human health
  • skin cancer
  • dna methylation
  • risk assessment
  • climate change