Genetic determinants of immune-related adverse events in patients with melanoma receiving immune checkpoint inhibitors.

Noha Abdel-WahabAdi DiabRobert K YuAndrew FutrealLindsey A CriswellJean H TayarRamona DaduVickie ShannonSanjay S SheteMaria E Suarez-Almazor

Published in: Cancer immunology, immunotherapy : CII (2021)

Several genetic variants associated with irAEs were identified. Additional larger studies are needed to validate these findings and establish their potential functional relevance.

Keyphrases

genome wide
case control
copy number
human health
skin cancer
dna methylation
risk assessment
climate change