Molecular Basis of Extramural Vascular Invasion (EMVI) in Colorectal Carcinoma.
Swati SonalVikram DeshpandeDavid T TingJames C CusackAparna R ParikhAzfar NeyazAmaya PankajMartin S TaylorAnne M DinauxLieve G J LeijssenChloe BoudreauJoseph J LocascioHiroko KunitakeRobert N GoldstoneLiliana G BordeianouChristy E CauleyRocco RicciardiDavid L BergerPublished in: Annals of surgical oncology (2022)
There is a generalized blunting of immune response in EMVI positive colorectal carcinoma, which may contribute to a worse prognosis. Tumor-associated macrophages seem to play the most significant role in determining EMVI.