Pain-related increase in serotonin transporter gene methylation associates with emotional regulation in 4.5-year-old preterm-born children.

Livio ProvenziMonica FumagalliGiunia Scotto di MinicoRoberto GiordaFrancesco MorandiIda SirgiovanniPaola SchiavolinFabio MoscaRenato BorgattiRosario Montirosso

Published in: Acta paediatrica (Oslo, Norway : 1992) (2019)

These findings contribute to highlight how epigenetic regulation of serotonin transporter gene in response to NICU pain exposure contributes to long-lasting programming of anger regulation in preterm children.

Keyphrases

low birth weight
chronic pain
genome wide
gestational age
preterm infants
young adults
pain management
preterm birth
neuropathic pain
copy number
dna methylation
genome wide identification
spinal cord
gene expression
drug induced