Yes-Associated Protein Targets the Transforming Growth Factor β Pathway to Mediate High-Fat/High-Sucrose Diet-induced Arterial Stiffness.
Yanan LiuMengke LiXue LvKaiwen BaoXiao Yu TianLei HeLei ShiYi ZhuDing AiPublished in: Circulation research (2022)
This study provides a new mechanism by which smooth muscle cell YAP regulates the TGFβ pathway and a potential therapeutic target in metabolic syndrome-associated arterial stiffness.