Influence of Comorbid Psychiatric Disorders on the Risk of Development of Alcohol Dependence by Genetic Variations of ALDH2 and ADH1B.

Mitsuru ItohTomoko YonemotoFumihiko UenoChie IwaharaYosuke YumotoHideki NakayamaHitoshi MaesatoMitsuru KimuraSachio Matsushita

Published in: Alcoholism, clinical and experimental research (2020)

This study suggested that (i) ADHD is a risk factor for AUD, consistent with previous reports; (ii) agoraphobia and panic disorder may have deterrent effects against the development of AUD in individuals with inactive ALDH2, probably attributable to the similarity between the symptoms of agoraphobia and panic disorder and the adverse reactions to consumption of alcohol in subjects with inactive ALDH2.

Keyphrases

attention deficit hyperactivity disorder
alcohol consumption
autism spectrum disorder
working memory
genome wide
adverse drug
emergency department
sleep quality
depressive symptoms