Pharmaceutical Design Of A Formulation Of Enrofloxacin-Alginate And Its Strategic Dosage To Achieve Mutant Prevention Pk/Pd Ratios In Broiler Chickens.

Contrary to expectations, groups Enroad-lib and Enrobolus failed to achieve the desired PK/PD ratios when the breakpoint was established at 0.5 µg/mL but did so when MIC was set at 0.1 µg/mL. In contrast, EADBsbolus and Enrow&f achieved an adequate AUC0-24/MIC ratio for both MIC levels.