Genistein Exposure Interferes with Pharmacokinetics of Celecoxib in SD Male Rats by UPLC-MS/MS.
Xiang ZhengJian WenTeng-Hui LiuQiu-Geng Ou-YangJian-Ping CaiHong-Yu ZhouPublished in: Biochemistry research international (2017)
Genistein inhibits the conversion of celecoxib in vitro and in vivo. So, the dosage of celecoxib should be adjusted if it was used associated with genistein.