Markers of arterial stiffness and urinary metabolomics in young adults with early cardiovascular risk: the African-PREDICT study.
Wessel L du ToitRuan KrugerLebo Francina Gafane-MatemaneAletta Elisabeth SchutteRoan LouwCatharina Martha Cornelia MelsPublished in: Metabolomics : Official journal of the Metabolomic Society (2023)
In a group with increased CVD risk, markers of arterial stiffness were negatively associated with metabolites related to AAA and BCAA as well as energy metabolism and oxidative stress. Our findings may suggest that metabolic adaptations may be at play in response to increased CVD risk to maintain cardiovascular integrity.