1,8 cineole protects type 2 diabetic rats against diabetic nephropathy via inducing the activity of glyoxalase-I and lowering the level of transforming growth factor-1β.

Published in: Journal of diabetes and metabolic disorders (2022)

Cin ameliorated diabetic nephropathy via reduction of TGF-1β following to decrease the formation of different glycation products, oxidative stress, and inflammatory process with the induction of the activity of glyoxalase-I in type 2 diabetic rats.

Keyphrases

diabetic rats
diabetic nephropathy
oxidative stress
transforming growth factor
epithelial mesenchymal transition
ischemia reperfusion injury
dna damage
induced apoptosis
heat shock