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Association Between the Prothrombin Time-International Normalized Ratio and Concomitant Use of Antibiotics in Warfarin Users: Focus on Type of Antibiotic and Susceptibility of Bacteroides fragilis to Antibiotics.

Tatsuya YagiTakafumi NaitoAyami KatoKensho HiraoJunichi Kawakami
Published in: The Annals of pharmacotherapy (2020)
Concomitant use of FQs, or of antibiotics to which B fragilis is susceptible is associated with higher risk of excessive anticoagulation. These findings would contribute to safe and proper antibiotic treatment in warfarin users.
Keyphrases
  • atrial fibrillation
  • venous thromboembolism
  • direct oral anticoagulants
  • oral anticoagulants
  • weight gain
  • body mass index
  • smoking cessation