Efforts of subthalamic nucleus deep brain stimulation on cognitive spectrum: From explicit to implicit changes in the patients with Parkinson's disease for 1 year.
ZhiFei YouYi-Ying WuRong WuZhi-Xiang XuXi WuXiao-Ping WangPublished in: CNS neuroscience & therapeutics (2020)
STN-DBS as a neuromodulatory tool in the Chinese PD population not only improves motor symptoms but also cognitive function to a certain extent, such as the decline of executive function and verbal fluency. The explicit cognitive decline was significantly quicker than that in patients on medication therapy. The improvement of visiospatial function was also noted. Implicit memory impairment during the 1-year follow-up period was not observed.
Keyphrases
- deep brain stimulation
- cognitive decline
- parkinson disease
- obsessive compulsive disorder
- mild cognitive impairment
- end stage renal disease
- working memory
- ejection fraction
- newly diagnosed
- chronic kidney disease
- prognostic factors
- emergency department
- stem cells
- physical activity
- quality improvement
- mesenchymal stem cells
- cell therapy